Free Download MicroRNA Interference Technologies
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Book Details :
Published on: 2009-06-11
Released on: 2009-06-11
Original language:
MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of around 22-nucleotides long, have rapidly emerged as one of the key governors of the gene expression regulatory program in cells of varying species, with ever-increasing implications in the control of the fundamental biological processes and in the pathogenesis of adult humans. The exciting findings in this field have inspired us with a premise and a promise that miRNAs will ultimately be taken to the heart for therapy of human disease. While miRNAs have been considered potential therapeutic targets for disease treatment, it remains obscured what strategies we can use to achieve the goal. In the past years, we have witnessed a rapid evolving of many creative, innovative, inventive strategies and methodologies pertinent to miRNA research and applications. These technologies have convincingly demonstrated their efficacy and reliability in producing gain-of-function or loss-of-function of miRNAs through targeting miRNA expression/biogenesis/function, providing new tools for elucidating miRNA functions and opening up a new avenue for the development of new agents targeting miRNAs for therapeutic aims. The present book provides comprehensive descriptions of these technologies and their applications to miRNA research and to new drug design for miRNA-related diseases. It starts with an overview of up-to-date knowledge of miRNA biology and the potential of miRNAs as therapeutic targets for human disease, followed by an introduction of the new concept of miRNA interference (miRNAi) and the perspectives of miRNAi technologies in general terms. In the following, each chapter introduces one of the miRNAi technologies with detailed descriptions of state-of-the-art design, procedures, principles and applications to basic research, R and D and clinical therapy. RNA Interference - Review - InvivoGen RNA Interference - Review. RNA interference (RNAi) is one of the most exciting discoveries of the past decade in functional genomics. RNAi is rapidly becoming an ... MicroRNA-141 suppresses prostate cancer stem cells and ... Article Open. MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes. Can Liu 1 2 Genomics Applications & Technologies Bio-Rad Explore different aspects of genomics from functional genomics and biomarker discovery to mutation analysis gene expression transfection and epigenetics. MicroRNA in TLR signaling and endotoxin tolerance - Nature Review. Cellular & Molecular Immunology (2011) 8 388403; doi:10.1038/cmi.2011.26; published online 8 August 2011. MicroRNA in TLR signaling and endotoxin tolerance The Host Shapes the Gut Microbiota via Fecal MicroRNA The host gut microbiota varies across species and individuals but is relatively stable over time within an individual. How the host selectively shapes the micro Keystone Symposia Scientific Conferences on Biomedical ... TERM: USE: EXAMPLE: AND: Used to narrow your search. Cancer AND MicroRNA - would return any meetings/abstracts with both 'Cancer' and 'MicroRNA'. If just one of these ... Functional Genomics & RNAi - Sigma-Aldrich We provide leading functional genomics technologies including RNA interference (RNAi) tools for gene silencing (siRNA esiRNA shRNA miRNA) and cutting-edge systems ... Dicer - Wikipedia Dicer also known as endoribonuclease Dicer or helicase with RNase motif is an enzyme that in humans is encoded by the DICER1 gene. Being part of the RNase III ... LAT - What does LAT stand for? The Free Dictionary Acronym Definition; LAT: Los Angeles Times: LAT: Latin: LAT: Latvia: LAT: Large Area Telescope (NASA) LAT: Latitude: Lat: Lateral: LAT: Local Area Transport: LAT ... Brands - Home EuroClone S.p.A. Large array of products for site specific transgenics iPSC generation and stem cell research.
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